DiaPlexC™ M.Avium/M.Intracellulare Detection Kit

The DiaPlexC™ M.Avium/M.Intracellulare Detection Kit is designed to detect Mycobacterium Avium and mycobacterium Intracellulare of Non-Tuberculosis Mycobacterium using the Multiplex PCR technology which can detect multiple specific target genes in a single PCR.

Pathogen Information

Mycobacterium avium and Mycobacterium intracellulare complex (MIC) is the atypical mycobacterium most commonly associated with human disease. MIC is primarily a pulmonary pathogen that affects individuals who are immune compromised (eg, from AIDS, hairy cell leukemia, immunosuppressive chemotherapy). In this clinical setting, MIC has been associated with osteomyelitis; tenosynovitis; synovitis. MIC comprises two genetically distinct but difficult to discriminate species. M.avium predominates (87-98%) in AIDS patients with no anti-retroviral therapy and M.intracellulare is more frequent among non-AIDS patients.

Detection Technology

Conventional PCR


Nasopharyngeal swab, Nasopharyngeal aspirate
Bronchoalveolar lavage (BAL), Nasal aspirates or Sputum
Target Organisms
Mycobacterium Avium
Mycobacterium Intracellulare
Analytical Sensitivity
102 Copies


HotStart PCR System: Ultra highly-specific and sensitive results.
DnaFree™ System: No host genomic DNA contamination.
UDG System: No carryover contamination.
Multiplex PCR: Multiple targets in a single reaction.
Reliable System: Automatic PCR control.
Easy-to-use Master Mix: Just add the template and primer.
CE Certification.


2X Multiplex PCR Smart Mix
Primer Mixture
Standard Marker
Control Templates
Nuclease-free Water


1. The NTM Handbook: A Guide for Patients with Nontuberculous Mycobacterial Infections Including MAC

2. Horsburgh CR Jr. Epidemiology of Mycobacterium avium complex. In: Korvick JA, Benson CA, eds. Mycobacterium avium Complex Infection: Progress in Research and Treatment. New York, NY: Marcel Dekker; 1996:1-22.

3. Tortoli E. Impact of genotypic studies on mycobacterial taxonomy: the new mycobacteria of the 1990s. Clin Microbiol Rev. 2003;16:319-354.

4. Griffith, David E.; Aksamit, Timothy; & A. Brown-Elliott, Barbara et al. (2007). American Thoracic Society Guidelines: Diagnosis, Treatment and Prevention of Nontuberculous Mycobacterial Diseases. Am. J. Respiratory and Critical Care Medicine, Vol. 175, pp. 367-417.

5. Grange, J. M. (2007). « Environmental mycobacteria ». In Greenwood, David; Slack, Richard; Peitherer, John; & Barer, Mike (Eds.), Medical Microbiology (17th ed.), pp. 221-227. Elsevier. ISBN 978-0-443-10209-7. Evans AJ, Crisp AJ, H ubbard RB, Colville A, Evans SA, Johnston IDA. Pulmonary Mycobacterium kansasii infection: comparison of radiological appearances with pulmonary tuberculosis. Thorax. 1996;51:1243-1247