DiaPlexC™ MTB/M.bovis Detection Kit is designed to detect mycobacterium tuberculosis and mycobacterium bovis using multiplex PCR technology which can detect multiple specific target genes in a single reaction PCR.
Mycobacterium tuberculosis (TB) is one of the most ubiquitously found infectious agents around the world, especially in developing countries causing pathogenesis of 8 million and the death of 2 million people each year. There is however a prevention method, the BCG(Bacillus Calmette-Guerin) TB vaccination, but it’s disadvantage is that it can not protect after 5 years from immunization, and there is also a possibility of causing diagnostic error for actual TB-infected patients by showing a false-positive result in the tuberculin test.
Nasopharyngeal swab, Nasopharyngeal aspirate
Bronchoalveolar lavage (BAL), Nasal aspirates or Sputum
Mycobacterium Tuberculosis (MTB)
Mycobacterium bovis (M.bovis)
HotStart PCR System: Ultra highly-specific and sensitive results.
DnaFree™ System: No host genomic DNA contamination.
UDG System: No carryover contamination.
Multiplex PCR: Multiple targets in a single reaction.
Reliable System: Automatic PCR control.
Easy-to-use Master Mix: Just add the template and primer.
2X Multiplex PCR Smart Mix
1.”Mycobacterium tuberculosis” Sanger institute. 2007-03-29http://www.sanger.ac.uk/Projects/M_tuberculosis/. Retrieved 2008-11-16
2.Frothingham R, Meeker-Meeker-O’Connell WA. (1998). « Genetic diversity in the Mycobacterium tuberculosis complex based on variable numbers of tandem DNA repeats. ». Microbiology 144 (Pt 5): 1189–96.
3.Teo, SS; Shingadia, DV (2006 Jun). « Does BCG have a role in tuberculosis control and prevention in the United King dom? ». Archives of Disease in Childhood 91 (6): 529–31.