DiaPlexC™ MTC (Mycobacterium tuberculosis complex)/NTM (Non-Tuberculosis Mycobacteria Detection Kit

The DiaPlexC™ MTC/NTM Detection Kit is designed to detect single infection and co-infection of MTC&NTM using multiplex PCR technology which can detect multiple specific target genes in a single PCR.

Pathogen Information

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species and the causative agent of most cases of tuberculosis. Along with MTB, 5 other species, which are generally known as Mycobacterium tuberculosis complex (MTC), are regarded as common infectious agents causing tuberculosis. That is why it is necessary to detect MTC, along with MTB. Additionally, Non-tuberculosis Mycobacteria (NTM) usually causes lung infections that mimic tuberculosis resulting in a potential misdiagnosis. Thus, the identification of a single infecion or co-infection of MTC and NTM is required for appropriate treatment.

Detection Technology

Conventional PCR

Specimens

Sputum, Gastric lavage, Blood, Body fluids
Tissue biopsy, Cultured or Isolated cells.

Target Organisms

Mycobacterium Tuberculosis Complex (MTC) of 5 species
Non-Tuberculosis Mycobacteria (NTM) of 20 species

Analytical Sensitivity

102-103 copies

Features

HotStart PCR System: Ultra highly-specific and sensitive results.
DnaFree™ System: No host genomic DNA contamination.
UDG System: No carryover contamination.
Multiplex PCR: Multiple targets in a single reaction.
Reliable System: Automatic PCR control.
Easy-to-use Master Mix: Just add the template and primer.
CE Certification.

Contents

2X Multiplex PCR Smart Mix
Primer Mixture
Standard Marker
Control Template
Nuclease-free Water

References

1.Korean J Clin Microbiol, Seong Deok Lee, Hye Young Lee, Hyun Chul Kim, Soo Young Kim, Mycobacterium tubercul osis and Nontuberculous Mycobacteria by PCR Assay

2.Ryan KJ, Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed.).MCGraw Hill

3.Sun-Pil Choi, M.D., Bong-Keun Lee, M.D.1, Jin-Hong Min, M.D., Jin-Hee Kim, M.D. Pathogenic Classification and Clinical characteristics of Nontuberculous Mycobacterial Pulmonary disease in a national tuberculosis Hospital.